POEMS syndrome is an acronym for: Polyneuropathy, Organomegaly, Endocrinopathy, M-protein, and Skin changes. POEMS syndrome is very rare . It is also known as Crow-Fukase syndrome, Takatsuki disease, or PEP syndrome.

Looking at the acronym for POEMS syndrome in more detail:

• Polyneuropathy - Multiple neuropathies, or diseases of the nerves.
• Organomegaly - Enlargement of the liver and spleen
• Endocrinopathy - Any disease resulting from disorder of an endocrine gland or glands
• M-protein - Abnormal protein antibody
• Skin changes - Including an increase in pigmentation and excess growth of hair, possibly caused by endocrine disease, esp. of the adrenal gland, and in women, disease of the ovaries.