A common grouping of symptoms of thyroid problems, Hypothyroidism is the disease state caused by insufficient thyroid hormone by the thyroid gland. There are several distinct causes for chronic hypothyroidism, the most common being Hashimoto's thyroiditis and hypothyroidism following radioiodine therapy for hyperthyroidism.
The severity of hypothyroidism varies widely. Some patients are classified as "subclinical hypothyroid" when only diagnostic findings show thyroid hormone abnormalities. Others have moderate symptoms that can be mistaken for other diseases and states. Advanced hypothyroidism may cause severe complications, the most serious one of which is myxedema.Signs and symptoms of hypothyroid
In both adults and children, hypothyroid symptoms vary. Here is a basic breakdown by age of underactive thyroid symptoms:adult symptoms of hypothyroidism
Thyroid hormone is very important to neural development in the neonatal period. A deficiency of thyroid hormones can lead to cretinism. For this reason it is important to detect and treat thyroid deficiency early. In Australia, the Netherlands and many other countries this is done by testing for TSH on the routine neonatal heel pricks performed by law on all new born babies.Hashimoto's thyroiditis
Sometimes called Hashimoto's Disease, this is part of the spectrum of auto-immune diseases and is related to Graves' disease, lymphocytic thyroiditis as well as other organ related auto-immune conditions such as Addison's disease, diabetes, premature menopause and vitiligo. Hashimoto's is a lymphocytic and plasmacytic thyroid inflammation that eventually destroys the thyroid. Patients require permanent thyroid replacement.Pituitary failure
Reduction or loss of TSH secretion by the pituitary is a rare cause of hypothyroidism. This constellation is usually referred to as "secondary hypothyroidism". Even rarer is tertiary hypothyroidism that is caused either by hypothalamic lesions or by interruption of signal transfer in the portal veins connecting the hypothalamus to the pituitary gland (Pickardt syndrome).Iatrogenic
Hypothyroidism may occur as an adverse reaction to lithium used in the treatment of mood disorders, and in response to interferon and IL-2 treatment (e.g. for cancer). It may also be a result of the antiarrhythmic amiodarone.
Surgery on the thyroid is generally done in a form that allows some hormone-producing tissue to remain. Nevertheless, some patients will need hormone supplementation after surgery.
Disclaimer: Information shared in this section is indicative. Please do not make any conclusion and we strongly recommend you to consult with your Doctor. Symptoms may vary with individual, geography, climate and lifestyle